Claus Wilke


Claus Wilke received a PhD in theoretical physics from the Ruhr-University of Bochum in Germany in 1999. He then went to Caltech as a postdoc in computational evolutionary biology under the supervision of Chris Adami. In the fall of 2005, Wilke joined The University of Texas at Austin as assistant professor. He is affiliated with the Section of Integrative Biology, the Center for Computational Biology and Bioinformatics, and the Institute for Cell and Molecular Biology. His main research interests are the molecular evolution of protein-coding genes and the evolution of RNA viruses.


T. Zhou, M. Weems, and C. O. Wilke (2009) Translationally optimal codons associate with structurally sensitive sites in proteins. Mol. Biol. Evol. 26:1571-1580.

D. A. Drummond and C. O. Wilke (2008). Mistranslation-induced protein misfolding as a dominant constraint on coding-sequence evolution. Cell 134:341-352.

J. D. Bloom, A. Raval, and C. O. Wilke (2007). Thermodynamics of neutral protein evolution. Genetics 175:255-266.